Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39753 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-DDX3 antibody (ab37160)

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • ATP dependent RNA helicase DDX3X
    • ATP-dependent RNA helicase DDX3X
    • CAP Rf
    • DBX
    • DDX14
    • DDX3X
    • DDX3X_HUMAN
    • DEAD (Asp Glu Ala Asp) box polypeptide 3 X linked
    • DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
    • DEAD box
    • DEAD box protein 3
    • DEAD box protein 3 X-chromosomal
    • DEAD box X isoform
    • DEAD box, X isoform
    • DEAD/H (Asp Glu Ala Asp/His) box polypeptide 3
    • DEAD/H box 3
    • DEAD/H box 3, X-linked
    • Helicase like protein 2
    • Helicase-like protein 2
    • HLP2
    • X isoform
    • X-chromosomal
    see all
  • Function
    ATP-dependent RNA helicase. Acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. Also involved in HIV-1 replication. Interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location.
  • Sequence similarities
    Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Cellular localization
    Nucleus speckle. Cytoplasm. Located predominantly in nuclear speckles and, at low levels, throughout the cytoplasm. Located to the outer side of nuclear pore complexes (NPC). Shuttles between the nucleus and the cytoplasm in a XPO1-dependent manner.
  • Information by UniProt

References

ab39753 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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