Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39753 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-DDX3 antibody (ab37160)

    Western blot

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • ATP dependent RNA helicase DDX3X
    • ATP-dependent RNA helicase DDX3X
    • CAP Rf
    • DBX
    • DDX14
    • DDX3X
    • DDX3X_HUMAN
    • DEAD (Asp Glu Ala Asp) box polypeptide 3 X linked
    • DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
    • DEAD box
    • DEAD box protein 3
    • DEAD box protein 3 X-chromosomal
    • DEAD box X isoform
    • DEAD box, X isoform
    • DEAD/H (Asp Glu Ala Asp/His) box polypeptide 3
    • DEAD/H box 3
    • DEAD/H box 3, X-linked
    • Helicase like protein 2
    • Helicase-like protein 2
    • HLP2
    • X isoform
    • X-chromosomal
    see all
  • FunctionATP-dependent RNA helicase. Acts as a cofactor for XPO1-mediated nuclear export of incompletely spliced HIV-1 Rev RNAs. Also involved in HIV-1 replication. Interacts specifically with hepatitis C virus core protein resulting in a change in intracellular location.
  • Sequence similaritiesBelongs to the DEAD box helicase family. DDX3/DED1 subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Cellular localizationNucleus speckle. Cytoplasm. Located predominantly in nuclear speckles and, at low levels, throughout the cytoplasm. Located to the outer side of nuclear pore complexes (NPC). Shuttles between the nucleus and the cytoplasm in a XPO1-dependent manner.
  • Information by UniProt

References for Human DDX3 peptide (ab39753)

ab39753 has not yet been referenced specifically in any publications.

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