Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      GSQAKDKERCVIS
    • Amino acids
      269 to 281

Specifications

Our Abpromise guarantee covers the use of ab22949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • Activator of G protein signaling
    • Activator of G protein signaling 1
    • Activator of G-protein signaling 1
    • AGS 1
    • AGS1
    • Dexamethasone induced ras related protein 1
    • Dexamethasone-induced ras protein 1
    • Dexamethasone-induced Ras-related protein 1
    • Dexras 1
    • MGC:26290
    • RAS dexamethasone induced 1
    • Ras protein, Dexamethasone-induced, 1
    • Ras related protein
    • RASD 1
    • Rasd1
    • RASD1_HUMAN
    see all
  • Function
    Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65.
  • Tissue specificity
    Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues.
  • Sequence similarities
    Belongs to the small GTPase superfamily. RasD family.
  • Post-translational
    modifications
    S-nitrosylation stimulates guanine-nucleotide exchange activity.
  • Cellular localization
    Cell membrane. Cytoplasm > perinuclear region. Nucleus.
  • Information by UniProt

References

ab22949 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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