Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      NGSYFDRGAKGGSRLC Amino acids 203 to 218 of human DFF40 (1,2)
    • Amino acids
      203 to 218

Specifications

Our Abpromise guarantee covers the use of ab8439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

General Info

  • Alternative names
    • CAD
    • Caspase activated deoxyribonuclease
    • Caspase activated DNase
    • Caspase activated nuclease
    • Caspase-activated deoxyribonuclease
    • Caspase-activated DNase
    • Caspase-activated nuclease
    • CPAN
    • Deoxyribonuclease III, caspase activated
    • DFF 40
    • DFF-40
    • DFF2
    • DFF40
    • Dffb
    • DFFB_HUMAN
    • Didff
    • DNA fragmentation factor 40 kDa subunit
    • DNA fragmentation factor subunit beta
    • DNA fragmentation factor, 40 Da, beta polypeptide (caspase activated DNase)
    • DNA fragmentation factor, 40 kD beta subunit
    • DNA fragmentation factor, 40 kD, beta polypeptide
    • DNA fragmentation factor, 40kDa, beta polypeptide (caspase activated DNase)
    • OTTHUMP00000003633
    see all
  • Function
    Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
  • Sequence similarities
    Contains 1 CIDE-N domain.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

References for Human DFFB peptide (ab8439)

ab8439 has not yet been referenced specifically in any publications.

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