Overview

Description

  • NatureSynthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab89389 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-DFFB antibody (ab69438)

  • Purity70 - 90% by HPLC.

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • CAD
    • Caspase activated deoxyribonuclease
    • Caspase activated DNase
    • Caspase activated nuclease
    • Caspase-activated deoxyribonuclease
    • Caspase-activated DNase
    • Caspase-activated nuclease
    • CPAN
    • Deoxyribonuclease III, caspase activated
    • DFF 40
    • DFF-40
    • DFF2
    • DFF40
    • Dffb
    • DFFB_HUMAN
    • Didff
    • DNA fragmentation factor 40 kDa subunit
    • DNA fragmentation factor subunit beta
    • DNA fragmentation factor, 40 Da, beta polypeptide (caspase activated DNase)
    • DNA fragmentation factor, 40 kD beta subunit
    • DNA fragmentation factor, 40 kD, beta polypeptide
    • DNA fragmentation factor, 40kDa, beta polypeptide (caspase activated DNase)
    • OTTHUMP00000003633
    see all
  • FunctionNuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
  • Sequence similaritiesContains 1 CIDE-N domain.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt

References for Human DFFB peptide (ab89389)

ab89389 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"