Human DNA Polymerase lambda peptide (ab23131)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-LGLPYREPAERDW
    • Amino acids563 to 571

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-DNA Polymerase lambda antibody (ab5954)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • BETA N
    • BETAN
    • DNA directed DNA polymerase lambda
    • DNA polymerase beta 2
    • DNA polymerase beta-2
    • DNA polymerase kappa
    • DNA polymerase kappa DNA polymerase beta N
    • DNA polymerase lambda
    • DNA polymerase lamda2
    • DPOLL_HUMAN
    • EC 2.7.7.7,EC 4.2.99.
    • FLJ46002
    • OTTHUMP00000020321
    • OTTHUMP00000020323
    • OTTHUMP00000059179
    • Pol beta2
    • POL KAPPA
    • Pol Lambda
    • POLKAPPA
    • POLL
    • Polymerase DNA directed lambda
    see all
  • FunctionRepair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  • Tissue specificityExpressed in a number of tissues. Abundant in testis.
  • Sequence similaritiesBelongs to the DNA polymerase type-X family.
    Contains 1 BRCT domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human DNA Polymerase lambda peptide (ab23131)

ab23131 has not yet been referenced specifically in any publications.

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