The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-DNA Polymerase lambda antibody (ab5954)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
DNA directed DNA polymerase lambda
DNA polymerase beta 2
DNA polymerase beta-2
DNA polymerase kappa
DNA polymerase kappa DNA polymerase beta N
DNA polymerase lambda
DNA polymerase lamda2
EC 220.127.116.11,EC 4.2.99.
Polymerase DNA directed lambda
FunctionRepair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Tissue specificityExpressed in a number of tissues. Abundant in testis.
Sequence similaritiesBelongs to the DNA polymerase type-X family. Contains 1 BRCT domain.
Post-translational modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.