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- Amino Acid Sequence
Amino acids 398 to 417 of human DR3 (1,2)
- Amino acids398 to 417
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-DR3 antibody (ab8411)
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Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
PBS with 0.1% BSA 0.02% sodium azide pH7.2
- FunctionReceptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
- Tissue specificityAbundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
- Sequence similaritiesContains 1 death domain.
Contains 4 TNFR-Cys repeats.
- Cellular localizationSecreted and Cell membrane.
Information by UniProt
References for Human DR3 peptide (ab8443)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"