Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab41752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Purity70 - 90% by HPLC.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General info

  • Alternative names
    • EAA2_HUMAN
    • EAAT2
    • Excitatory amino acid transporter 2
    • Excitotoxic amino acid transporter 2
    • Glial high affinity glutamate transporter
    • GLT 1
    • GLT1
    • Glutamate aspartate transporter II
    • Glutamate transporter 1
    • Glutamate/aspartate transporter II
    • SLC1A2
    • Sodium dependent glutamate aspartate transporter 2
    • Sodium-dependent glutamate/aspartate transporter 2
    • solute carrier family 1 (glial high affinity glutamate transporter), member 2
    • Solute carrier family 1 glial high affinity glutamate transporter member 2
    • Solute carrier family 1 member 2
    see all
  • FunctionTransports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
  • Sequence similaritiesBelongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A2 subfamily.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localizationMembrane.
  • Target information above from: UniProt accession P43004 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Human EAAT2 peptide (ab41752)

This product has been referenced in:
  • Potapenko ES  et al. Altered astrocyte glutamate transporter regulation of hypothalamic neurosecretory neurons in heart failure rats. Am J Physiol Regul Integr Comp Physiol 303:R291-300 (2012). Read more (PubMed: 22696576) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"