Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab39757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General info

  • Alternative names
    • Ecsit
    • ECSIT homolog
    • ECSIT protein
    • ECSIT_HUMAN
    • Evolutionarily conserved signaling intermediate in Toll pathway
    • Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
    • Evolutionarily conserved signaling intermediate in Toll pathways
    • Likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved
    • Protein SITPEC
    • Signaling intermediate in Toll pathway evolutionarily conserved
    • SITPEC
    • SITPEC protein
    see all
  • FunctionAdapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
  • Sequence similaritiesBelongs to the ECSIT family.
  • Cellular localizationCytoplasm. Nucleus. Mitochondrion.
  • Target information above from: UniProt accession Q9BQ95 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Human ECSIT peptide (ab39757)

ab39757 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"