Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    Blocking - Blocking peptide for Anti-ECSIT antibody (ab21288)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • Ecsit
    • ECSIT homolog
    • ECSIT protein
    • ECSIT_HUMAN
    • Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
    • Evolutionarily conserved signaling intermediate in Toll pathways
    • Likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved
    • Protein SITPEC
    • Signaling intermediate in Toll pathway evolutionarily conserved
    • SITPEC
    • SITPEC protein
    see all
  • Function
    Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
  • Sequence similarities
    Belongs to the ECSIT family.
  • Cellular localization
    Cytoplasm. Nucleus. Mitochondrion.
  • Information by UniProt

References

ab39757 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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