Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-RLVPPSKRRHKGSA
    • Amino acids529 to 542

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-EHD2 antibody (ab23935)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

General Info

  • Alternative names
    • EH domain containing 2
    • EH domain containing 3
    • EH domain containing protein 2
    • EH domain-containing protein 2
    • EHD 2
    • Ehd2
    • EHD2_HUMAN
    • EHD3
    • FLJ96617
    • PAST 2
    • PAST homolog 2
    • PAST2
    see all
  • FunctionPlays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP.
  • Tissue specificityHighly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.
  • Sequence similaritiesContains 1 EF-hand domain.
    Contains 1 EH domain.
  • DomainThe EH domain interacts with Asn-Pro-Phe (NPF) motifs of target proteins.
  • Cellular localizationCell membrane. Endosome membrane. Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin.
  • Information by UniProt

References for Human EHD2 peptide (ab45619)

ab45619 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab45619.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"