Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-RLVPPSKRRHKGSA
    • Amino acids
      529 to 542

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-EHD2 antibody (ab23935)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

General Info

  • Alternative names
    • EH domain containing 2
    • EH domain containing 3
    • EH domain containing protein 2
    • EH domain-containing protein 2
    • EHD 2
    • Ehd2
    • EHD2_HUMAN
    • EHD3
    • FLJ96617
    • PAST 2
    • PAST homolog 2
    • PAST2
    see all
  • Function
    Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP.
  • Tissue specificity
    Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.
  • Sequence similarities
    Contains 1 EF-hand domain.
    Contains 1 EH domain.
  • Domain
    The EH domain interacts with Asn-Pro-Phe (NPF) motifs of target proteins.
  • Cellular localization
    Cell membrane. Endosome membrane. Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin.
  • Information by UniProt

References

ab45619 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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