Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-PKEPSSYDFVYHYG
    • Amino acids
      707 to 720

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-ELMO2 antibody (ab2240)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • CED 12
    • Ced 12 homolog 2
    • CED 12 homolog A
    • CED 12A
    • CED-12
    • ced-12 homolog 2
    • CED12
    • CED12 homolog A
    • CED12, C. elegans, homolog of, 2
    • CED12A
    • ELMO 2
    • ELMO-2
    • ELMO2
    • ELMO2_HUMAN
    • Engulfment and cell motility 2
    • Engulfment and cell motility 2 (ced 12 homolog, C. elegans)
    • Engulfment and cell motility gene 2
    • Engulfment and cell motility protein 2
    • FLJ11656
    • hCED 12A
    • hCED-12A
    • hCED12A
    • KIAA1834
    • OTTHUMP00000031762
    • PH domain protein CED12A
    • Protein ced 12 homolog A
    • Protein ced-12 homolog A
    see all
  • Function
    Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • Tissue specificity
    Widely expressed, with a higher expression in skeletal muscle, kidney and placenta.
  • Sequence similarities
    Contains 1 ELMO domain.
    Contains 1 PH domain.
  • Cellular localization
    Cytoplasm. Cytoplasm > cytosol. Membrane.
  • Information by UniProt

References

ab22879 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab22879.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up