The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-ELMO2 antibody (ab2240)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Ced 12 homolog 2
CED 12 homolog A
ced-12 homolog 2
CED12 homolog A
CED12, C. elegans, homolog of, 2
Engulfment and cell motility 2
Engulfment and cell motility 2 (ced 12 homolog, C. elegans)
Engulfment and cell motility gene 2
Engulfment and cell motility protein 2
PH domain protein CED12A
Protein ced 12 homolog A
Protein ced-12 homolog A
FunctionInvolved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Tissue specificityWidely expressed, with a higher expression in skeletal muscle, kidney and placenta.