Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • AccessionQ9Y6C2
    • SpeciesHuman
    • Molecular weight39 kDa including tags
    • Amino acids676 to 1016

Specifications

Our Abpromise guarantee covers the use of ab116414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF-TOF
  • Purity> 95 % by SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituent: 99% PBS

General info

  • Alternative names
    • Elastin microfibril interface located protein
    • Elastin microfibril interface located protein 1
    • Elastin microfibril interface-located protein 1
    • Elastin microfibril interfacer 1
    • EMIL1_HUMAN
    • EMILIN
    • EMILIN 1
    • EMILIN-1
    • Emilin1
    • gp115
    see all
  • FunctionMay be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
  • Tissue specificityDistributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver, ovary, colon, stomach, lymph node and spleen; adult heart, bladder, prostate, adrenal gland, mammary gland, placenta and kidney showed low expression whereas a series of other adult tissues, including skeletal muscle and different regions of adult brain show no expression.
  • Sequence similaritiesContains 1 C1q domain.
    Contains 1 collagen-like domain.
    Contains 1 EMI domain.
  • Cellular localizationSecreted > extracellular space > extracellular matrix. Found mainly at the interface between amorphous elastin and microfibrils.
  • Information by UniProt

Human EMILIN1 protein fragment images

  • 10% SDS-PAGE stained with Coomassie Blue (Lane 1), immunobloting with anti-6xHis (Lane 2)

References for Human EMILIN1 protein fragment (ab116414)

ab116414 has not yet been referenced specifically in any publications.

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