Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab48695 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-ENT2 antibody (ab48595)

  • Form
    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • 36 kDa
    • 36 kDa nucleolar protein HNP36
    • Delayed-early response protein 12
    • DER12
    • ei-type
    • Equilibrative NBMPR-insensitive nucleoside transporter
    • Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter
    • Equilibrative nucleoside transporter 2
    • HNP36
    • Hydrophobic nucleolar protein
    • Hydrophobic nucleolar protein, 36 kDa
    • Nucleoside transporter
    • S29A2_HUMAN
    • SLC29A2
    • solute carrier family 29 (nucleoside transporters), member 29
    • Solute carrier family 29 member 2
    see all
  • Function
    Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine.
  • Tissue specificity
    Expressed in skeletal muscle, liver, lung, placenta, brain, heart, kidney and ovarian tissues.
  • Sequence similarities
    Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
  • Cellular localization
    Basolateral cell membrane. Nucleus membrane. Localized at the basolateral cell membrane in polarized MDCK cells.
  • Information by UniProt

References

ab48695 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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