Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-SGVESFDEGSSH
    • Amino acids811 to 822

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45513 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-EPS8 antibody (ab38329)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

General Info

  • Alternative names
    • Epidermal growth factor receptor kinase substrate 8
    • Epidermal growth factor receptor pathway substrate 8
    • EPS 8
    • EPS8
    • EPS8_HUMAN
    see all
  • FunctionUpon binding to EGF receptor enhances EGF-dependent mitogenic signals. Can bind multiple cellular targets.
  • Tissue specificityExpressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells.
  • Sequence similaritiesBelongs to the EPS8 family.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
  • DomainThe SH3 domain mediates interaction with SHB.
  • Post-translational
    modifications
    Phosphorylated by several receptor tyrosine kinases.
  • Information by UniProt

References for Human EPS8 peptide (ab45513)

ab45513 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab45513.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"