Human Estrogen Related Receptor gamma peptide (ab39779)

Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceDYEAGQHMEDPRR
    • Amino acids401 to 413

Specifications

Our Abpromise guarantee covers the use of ab39779 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Estrogen Related Receptor gamma antibody - ChIP Grade (ab16366)

    Neutralising

  • Purity> 90 % SDS-PAGE.
    This peptide is greater than 70% pure.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Double distilled water or equivalent after reconstitution.

General Info

  • Alternative names
    • DKFZp781L1617
    • ERR 3
    • ERR G2
    • ERR gamma 2
    • ERR gamma-2
    • ERR3
    • ERR3_HUMAN
    • ERRG 2
    • ERRG2
    • ERRgamma
    • ESRRG
    • Estrogen receptor related protein 3
    • Estrogen receptor-related protein 3
    • Estrogen-related receptor gamma
    • FLJ16023
    • KIAA0832
    • NR3B3
    • Nuclear receptor subfamily 3 group B member 3
    see all
  • FunctionOrphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements.
  • Tissue specificityExpressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.
  • Sequence similaritiesBelongs to the nuclear hormone receptor family. NR3 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Developmental stageExpressed at high levels in fetal brain and also in the fetal kidney, lung and liver.
  • Post-translational
    modifications
    Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity.
    Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human Estrogen Related Receptor gamma peptide (ab39779)

ab39779 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab39779.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"