Overview

  • Product nameHuman FGF6 protein fragment
  • DescriptionHuman FGF6 protein fragment

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceGTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQRRLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LFGVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQGT YIALSKYGRV KRGSKVSPIM TVTHFLPRI
    • Amino acids41 to 208

Specifications

Our Abpromise guarantee covers the use of ab50130 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Purity> 95 % by SDS-PAGE.
    Greater than 95% by SDS-PAGE.
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Sodium chloride, 10mM Sodium phosphate, pH 7.2
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

  • ReconstitutionCentrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use. Repeated freeze thaw cycles will result in some loss of activity.

General info

  • Alternative names
    • FGF 6
    • Fibroblast growth factor 6
    • Fibroblast growth factor 6 precursor
    • HBGF 6
    • HBGF6
    • HST 2
    • HST2
    see all
  • RelevanceFGF6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. The FGF6 gene displays oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.
  • Cellular localizationSecreted

References for Human FGF6 protein fragment (ab50130)

ab50130 has not yet been referenced specifically in any publications.

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