Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-KRRRTLLEQLDDDQ
    • Amino acids
      944 to 957

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23236 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-FNBP3 antibody (ab13774)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • Fas ligand associated factor 1
    • Fas ligand-associated factor 1
    • FBP 11
    • FBP11
    • FLAF 1
    • FLAF1
    • FNBP 3
    • Formin binding protein 11
    • Formin binding protein 3
    • Formin-binding protein 11
    • Formin-binding protein 3
    • HIP-10
    • HIP10
    • Huntingtin interacting protein A
    • Huntingtin interacting protein HYPA
    • Huntingtin yeast partner A
    • Huntingtin-interacting protein 10
    • Huntingtin-interacting protein A
    • HYPA
    • NY REN 6
    • NY REN 6 antigen
    • PR40A_HUMAN
    • Pre mRNA processing factor 40 homolog A
    • Pre-mRNA-processing factor 40 homolog A
    • PRP40 pre mRNA processing factor 40 homolog A
    • PRP40 pre mRNA processing factor 40 homolog A (S cerevisiae)
    • PRP40 pre mRNA processing factor 40 homolog A (yeast)
    • PRPF 40A
    • PRPF40A
    • Renal carcinoma antigen NY-REN-6
    see all
  • Function
    Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing.
  • Tissue specificity
    Expressed in the brain cortex (at protein level). Widely expressed.
  • Sequence similarities
    Belongs to the PRPF40 family.
    Contains 5 FF domains.
    Contains 2 WW domains.
  • Domain
    The WW domains are essential for localization to nuclear speckles.
  • Cellular localization
    Nucleus speckle. Nucleus matrix. Colocalizes with AKAP8L in the nuclear matrix.
  • Information by UniProt

References

ab23236 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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