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ab108678 Follicle Stimulating Hormone Human ELISA Kit is a immunoenzymatic colorimetric method for quantitative determination of Follicle Stimulating Hormone in serum.
Follicle Stimulating hormone (FSH) is a glycoprotein consisting of two subunits with an approximate molecular mass of 35,500 daltons. The alpha-subunit is similar to other pituitary hormones [luteinizing stimulating hormone (LH), thyroid stimulating hormone (TSH) and chorionic gonadotropin (hCG)] while the beta-subunit is unique. The beta-subunit confers the biological activity to the molecule. Stimulation by gonadotropin-releasing hormone (GnRH) causes release of FSH, as well as LH, from the pituitary and is transported by the blood to their sites of action, the testes or ovary. In men, FSH acts on the Sertoli cells of the testis, stimulating the synthesis of inhibin, which appears to specifically inhibit further FSH secretion, and androgen-binding protein. Thus, it indirectly supports spermatogenesis. In women, FSH acts on the granulosa cells of the ovary, stimulating steroidogensis. All ovulatory menstrual cycles have a characteristic pattern of FSH, as well as LH, secretion.
|Components||Identifier||1 x 96 tests|
|Anti-FSH conjugate||1 x 12ml|
|Coated Wells||12 strips of 8 wells||1 unit|
|Foil Cover||1 unit|
|FSH Control||1 x 1ml|
|FSH Standards||6 x 1ml|
|Stop Solution||1 x 15ml|
|Strip holder||1 unit|
|TMB Substrate Solution||1 x 15ml|
|Wash solution 50x conc.||1 x 50ml|
Our Abpromise guarantee covers the use of ab108678 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Sandwich ELISA||Use at an assay dependent dilution.|
ab108678 has not yet been referenced specifically in any publications.