Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      GGPARSPSASTNC
    • Amino acids
      2 to 14

Specifications

Our Abpromise guarantee covers the use of ab23300 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • FKH L15
    • FKHL 15
    • FKHL15
    • Forkhead (Drosophila) like 15
    • Forkhead box E1
    • Forkhead box E2
    • Forkhead box protein E1
    • Forkhead box protein E2
    • Forkhead drosophila homolog like 15
    • Forkhead like 15
    • Forkhead related protein FKHL 15
    • Forkhead related protein FKHL15
    • Forkhead-related protein FKHL15
    • FOX E1
    • FOX E2
    • FOXE 1
    • FOXE 2
    • FOXE1
    • FOXE1_HUMAN
    • FOXE2
    • HFKH 4
    • HFKH4
    • HFKL 5
    • HFKL5
    • HNF-3/fork head-like protein 5
    • Thyroid transcription factor 2
    • TITF 2
    • TITF2
    • TTF 2
    • TTF-2
    • TTF2
    see all
  • Function
    Probable transcription factor. Could be involved in thyroid gland organogenesis.
  • Tissue specificity
    Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas.
  • Involvement in disease
    Defects in FOXE1 are the cause of Bamforth-Lazarus syndrome (BLS) [MIM:241850]. BLS is associated with thyroid agenesis, cleft palate and choanal atresia.
  • Sequence similarities
    Contains 1 fork-head DNA-binding domain.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab23300 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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