Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • AccessionP55316
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab19644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-FOXG1 antibody - ChIP Grade (ab18259), Anti-FOXG1 antibody [mAbcam 51774] (ab51774)

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • BF-1
    • BF-2
    • BF1
    • BF2
    • Brain factor 1
    • Brain factor 2
    • FHKL
    • FKH2
    • FKHL1
    • FKHL2
    • FKHL3
    • FKHL4
    • Forkhead box protein G1
    • Forkhead box protein G1A
    • Forkhead box protein G1B
    • Forkhead box protein G1C
    • Forkhead like 1
    • Forkhead like 2
    • Forkhead like 3
    • Forkhead like 4
    • Forkhead-related protein FKHL1
    • Forkhead-related protein FKHL2
    • Forkhead-related protein FKHL3
    • FOXG1
    • FOXG1_HUMAN
    • FOXG1A
    • FOXG1B
    • FOXG1C
    • HBF 1
    • HBF G2
    • hBF-2
    • HBF2
    • HFK1
    • HFK2
    • HFK3
    • KHL2
    • Oncogene QIN
    • QIN
    see all
  • FunctionTranscription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
  • Tissue specificityExpression is restricted to the neurons of the developing telencephalon.
  • Involvement in diseaseDefects in FOXG1 are the cause of congenital variant of Rett syndrome (RTTCV) [MIM:613454]. RTTCV is a severe neurodevelopmental disorder with features of classic Rett syndrome but earlier onset in the first months of life. Clinical features include progressive microcephaly, hypotonia, irresponsiveness and irritability in the neonatal period, mental retardation, psychomotor regression and stereotypical movements.
  • Sequence similaritiesContains 1 fork-head DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human FOXG1 peptide (ab19644)

ab19644 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"