Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-DNINWSQFIPELQ
    • Amino acids751 to 763

Specifications

Our Abpromise guarantee covers the use of ab23253 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • FKHL16
    • Forkhead box M1
    • Forkhead box protein M1
    • forkhead like 16
    • Forkhead-related protein FKHL16
    • FOX M1
    • Foxm1
    • FOXM1_HUMAN
    • FOXM1B
    • Hepatocyte nuclear factor 3 forkhead homolog 11
    • HFH-11
    • HFH11
    • HNF-3/fork-head homolog 11
    • HNF3
    • INS1
    • M phase phosphoprotein 2
    • M-phase phosphoprotein 2
    • MPHOSPH2
    • MPM-2 reactive phosphoprotein 2
    • MPP2
    • PIG29
    • TGT3
    • Transcription factor Trident
    • Trident
    • WIN
    • Winged-helix factor from INS-1 cells
    • Winged-helix factor from INS1 cells
    see all
  • FunctionTranscriptional activatory factor. May play a role in the control of cell proliferation.
  • Tissue specificityExpressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis.
  • Sequence similaritiesContains 1 fork-head DNA-binding domain.
  • Developmental stageEmbryonic expression pattern: liver, lung, intestine, kidney, urinary tract; adult expression pattern: intestine, colon, testis and thymus.
  • DomainWithin the protein there is a domain which acts as a transcriptional activator. Insertion of a splicing sequence within it inactivates this transcriptional activity, as it is the case for isoform 4.
  • Post-translational
    modifications
    Phosphorylated in M (mitotic) phase.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human FOXM1 peptide (ab23253)

ab23253 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab23253.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"