The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Forkhead box M1
Forkhead box protein M1
forkhead like 16
Forkhead-related protein FKHL16
Hepatocyte nuclear factor 3 forkhead homolog 11
HNF-3/fork-head homolog 11
M phase phosphoprotein 2
M-phase phosphoprotein 2
MPM-2 reactive phosphoprotein 2
Transcription factor Trident
Winged-helix factor from INS-1 cells
Winged-helix factor from INS1 cells
FunctionTranscriptional activatory factor. May play a role in the control of cell proliferation.
Tissue specificityExpressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis.
DomainWithin the protein there is a domain which acts as a transcriptional activator. Insertion of a splicing sequence within it inactivates this transcriptional activity, as it is the case for isoform 4.
Post-translational modificationsPhosphorylated in M (mitotic) phase.