Overview

  • Product name
    Human FRAT1 peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-AQLRTGDGVLVPGS
    • Amino acids
      266 to 279

Specifications

Our Abpromise guarantee covers the use of ab22919 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • FRAT 1
    • frequently rearranged in advanced T cell lymphomas
    • Frequently rearranged in advanced T-cell lymphomas
    • GSK 3 binding protein FRAT1
    • proto oncogene FRAT1
    see all
  • Relevance
    The protein encoded by the FRAT1 gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and also positively regulates the Wnt signaling pathway. It may play a role in tumor progression and in lymphomagenesis.
  • Cellular localization
    Cytoplasmic

References

ab22919 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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