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Accession number: NM_000817.
The HsGAD67 primers and probe can be used to quantify a control locus in chromatin immunoprecipitation (ChIP) assays with chromatin prepared from human cells.
GAD1 (Glutamic acid decarboxylase) is expressed in neurons but silenced in most other cell types. The primers and probe are located in exon 1, within 1 kb of the transcription start site. In most cell types GAD1 is enriched with histone modifications associated with silencing (e.g. Histone H3 K9 mono methylation, see image with ab9045). Whereas it shows low levels of histone modifications associated with active gene transcription such as Histone H3 K9 acetylation (see image with ab4441).
ab85780 has not yet been referenced specifically in any publications.
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