The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions. - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer. - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent. - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised. - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
14 kDa laminin-binding protein
14 kDa lectin
Beta galactoside binding lectin
Beta galactoside binding lectin L 14 I
beta galactoside binding protein
Beta-galactoside-binding lectin L-14-I
Lactose binding lectin 1
Lactose-binding lectin 1
Lectin galactoside binding soluble 1
Lectin galactoside-binding soluble 1
Lgals1 lectin galactose binding soluble 1
MAPK activating protein MP12
Putative MAPK activating protein MP12
Putative MAPK-activating protein PM12
S Lac lectin 1
S-Lac lectin 1
FunctionMay regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.
Tissue specificityExpressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
Sequence similaritiesContains 1 galectin domain.
Cellular localizationSecreted > extracellular space > extracellular matrix.