Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Sequenceab89487 is purified using conventional chromatography techniques.
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab89487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % by SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

General info

  • Alternative names
    • 35 kDa lectin
    • Carbohydrate binding protein 35
    • Carbohydrate-binding protein 35
    • CBP 35
    • CBP35
    • Gal-3
    • GAL3
    • Galactose-specific lectin 3
    • Galactoside-binding protein
    • GALBP
    • Galectin 3 internal gene,included
    • Galectin-3
    • Galectin3
    • GALIG
    • GBP
    • IgE binding protein
    • IgE-binding protein
    • L 31
    • L 34
    • L-31
    • L-34 galactoside-binding lectin
    • L31
    • Laminin-binding protein
    • Lectin L-29
    • Lectin, galactose binding, soluble 3
    • LEG3_HUMAN
    • LGALS2
    • LGALS3
    • MAC 2 antigen
    • Mac-2
    • Mac-2 antigen
    • MAC2
    • Macrophage galactose-specific lectin
    • MGC105387
    see all
  • FunctionGalactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.
  • Tissue specificityA major expression is found in the colonic epithelium. It is also abundant in the activated macrophages.
  • Sequence similaritiesContains 1 galectin domain.
  • Cellular localizationNucleus. Cytoplasmic in adenomas and carcinomas. May be secreted by a non-classical secretory pathway and associate with the cell surface.
  • Information by UniProt

Human Galectin 3 full length protein images

  • 15% SDS-PAGE showing ab89487 at approximately 28.3kDa (3µg).

References for Human Galectin 3 full length protein (ab89487)

This product has been referenced in:
  • Jiang K  et al. Galectin-3 regulates desmoglein-2 and intestinal epithelial intercellular adhesion. J Biol Chem 289:10510-7 (2014). Read more (PubMed: 24567334) »

See 1 Publication for this product

Product Wall

Thank you for contacting us. The concentration for ab89487 was determined by Bradford assay. I hope this helps, please let me know if you need any additional information or assistance.

Thank you for your response. We are expecting the new stock any time in our US office and hopefully we can dispatch the item this week sometimes. Thank you for your understanding and patien

Thank you for your patience. This is to let you know that I have placed a new order for you - for one vial of ab89487 as a free of charge replacement and the new order number is 978590. Currently, we are waiting for the new stock and as soon as we ...

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Thank you for getting back to me. I completely understand your frustration and try to do my best to solve this problem as soon as possible. I would like to update you on this issue: The lot number is an identification number for the syn...

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Thank you for your response. We can provide new vial from the same lot. After reviewing and discussing this issue carefully with the originator, I would like to clarify that both Abcam  batch numbers GR 46331-3 (two free of charge replacement vials No:...

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Thank you for your enquiry and for getting back to me. I am very pleased to hear that that the two replacement vials from the very new batch worked fine. Just to clarify the new vials were specifically prepared for you and the new batch is stil...

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Thank you for your recent message. Could you please confirm if the replacement vials which were arranged on Order NO: 959627 worked as expected or not? This information would be very important for us and for our Lab. Did you purchase the new vial (...

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Thank you for getting back to me. We will very shortly send you 2 vials from our new batch as free of charge replacements. We sincerely apologize for any inconvenience caused and thank you for bringing this matter to our attention. ...

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Thank you for providing some further details. I have contacted you on the 27th September but still not heard from you. To see whether it was an isolated case, we re-verified our previous tests and tested other vials from the same lot. We believ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"