Human gamma Actin exon 6 ChIP Primer Set (ab85785)

Overview

  • Product nameHuman gamma Actin exon 6 ChIP Primer Set
  • Product overview

    Accession number: NG 011433.
    The ACT3 primers can be used to quantify a control locus in chromatin immunoprecipitation (ChIP) assays with chromatin prepared from human cells.

    Gamma actin is a constitutively expressed gene. The primers are located in exon 6 of the gamma actin gene, close to the 3` end of the gene. Together with the HsACT1 and HsACT2 primers these primers can be used to determine the abundance of a modification (e.g. Histone H3 K4 mono methylation, see image with ab8895) or a factor (e.g. RNA polymerase II, see image with ab26721) over the gamma actin locus.

Properties

  • RelevanceActins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. In vertebrates there are three main groups of actin isoforms, alpha, beta and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Defects in ACTG1 are the cause of non-syndromic sensorineural deafness autosomal dominant type 20 (DFNA20) [MIM:604717]; also called autosomal dominant deafness type 26 (DFNA26).
  • Cellular localizationCytoplasmic
  • Alternative names
    • ACT
    • ACTG
    • Actin, cytoplasmic 2
    • Actin, gamma 1 propeptide
    • Cytoskeletal gamma actin
    • Deafness, autosomal dominant 20
    • Deafness, autosomal dominant 26
    • DFNA20
    • DFNA26
    see all

References for Human gamma Actin exon 6 ChIP Primer Set (ab85785)

ab85785 has not yet been referenced specifically in any publications.

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