Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab41462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General info

  • Alternative names
    • EC 6.3.2.2
    • Gamma ECS
    • Gamma GCS
    • Gamma glutamylcysteine synthetase
    • Gamma-ECS
    • Gamma-glutamylcysteine synthetase
    • GCL
    • GCLC
    • GCLM
    • GCS
    • GCS Heavy Chain
    • GLCL
    • GLCLC
    • GLCLR
    • Glutamate cysteine ligase catalytic subunit
    • Glutamate cysteine ligase (gamma glutamylcysteine synthetase) regulatory (30.8kD)
    • Glutamate cysteine ligase catalytic subunit
    • Glutamate cysteine ligase modifier subunit
    • Glutamate cysteine ligase regulatory protein
    • Glutamate cysteine ligase regulatory subunit
    • Glutamate--cysteine ligase catalytic subunit
    • GSC light chain
    • GSH1_HUMAN
    see all
  • PathwaySulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.
  • Involvement in diseaseDefects in GCLC are the cause of hemolytic anemia (HAGGSD) [MIM:230450].
  • Sequence similaritiesBelongs to the glutamate--cysteine ligase type 3 family.
  • Target information above from: UniProt accession P48506 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Human GCLC peptide (ab41462)

ab41462 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab41462.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"