Human GDF8 / Myostatin protein fragment (ab50097)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceDFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab50097 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Inhibition Assay

    SDS-PAGE

    Functional Studies

  • Purity> 95 % by SDS-PAGE.
    Greater than 98% by SDS-PAGE and HPLC analyses.
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

  • ReconstitutionCentrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

General info

  • Alternative names
    • GDF 8
    • GDF-8
    • GDF8_HUMAN
    • Growth differentiation factor 8
    • Growth/Differentiation Factor 8
    • MSTN
    • myostatin
    • OTTHUMP00000163498
    see all
  • FunctionActs specifically as a negative regulator of skeletal muscle growth.
  • Sequence similaritiesBelongs to the TGF-beta family.
  • Cellular localizationSecreted.
  • Target information above from: UniProt accession O14793 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Human GDF8 / Myostatin protein fragment (ab50097)

ab50097 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

These two proteins are the same, except for the reconstitution instructions (water versus 20 mM Hcl). Both should work equally well in inhiibiting MPC-11 cell growth.

I hope this information is helpful to ...

Read More

Thank you for your recent telephone enquiry. I am pleased to confirm I have obtained the original testing procedure for inhibition assays using ab50097 GDF8 / Myostatin protein. Cytotoxicity Assay for h-Myostatin using MPC-11 cells Procedur...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"