Human GDF8 / Myostatin protein fragment (ab63300)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Sequence MG NENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVKVTDTP KRSRR KLN
    • Amino acids24 to 266

Specifications

Our Abpromise guarantee covers the use of ab63300 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Purity> 95 % by SDS-PAGE.

  • FormLiquid
  • Additional NotesProduct is NOT sterile! Please filter the product by an appropriate sterile filter before using it in cell culture.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM Sodium chloride, 20mM Tris, pH 8

General info

  • Alternative names
    • GDF 8
    • GDF-8
    • GDF8_HUMAN
    • Growth differentiation factor 8
    • Growth/Differentiation Factor 8
    • MSTN
    • myostatin
    • OTTHUMP00000163498
    see all
  • FunctionActs specifically as a negative regulator of skeletal muscle growth.
  • Sequence similaritiesBelongs to the TGF-beta family.
  • Cellular localizationSecreted.
  • Target information above from: UniProt accession O14793 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Human GDF8 / Myostatin protein fragment images

  • LANES:
    1. MW marker – 14, 21, 31, 45, 66, 97 kDa
    2. reduced and heated sample, 7µg/lane
    3. non-reduced and non-heated sample, 7µg/lane

References for Human GDF8 / Myostatin protein fragment (ab63300)

ab63300 has not yet been referenced specifically in any publications.

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