Human GDNF Receptor alpha 2 peptide (ab39769)

Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-GDNF Receptor alpha 2 antibody (ab8027)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • GDNF family receptor alpha 2
    • GDNF family receptor alpha-2
    • GDNF receptor alpha-2
    • GDNF receptor beta
    • GDNFR beta
    • GDNFR-alpha-2
    • GDNFR-beta
    • GDNFRB
    • GFR alpha 2
    • GFR-alpha-2
    • GFRA 2
    • Gfra2
    • GFRA2_HUMAN
    • Glial cell line derived neurotrophic factor family receptor alpha2b
    • Glial cell line derived neurotrophic factor receptor beta
    • Neurturin receptor alpha
    • NRTNR alpha
    • NRTNR-alpha
    • NTNR alpha
    • NTNR-alpha
    • NTNRA
    • PI linked cell surface accessory protein
    • PI linked cell-surface accessory protein
    • RET ligand 2
    • RETL 2
    • RETL2
    • TGF beta related neurotrophic factor receptor 2
    • TGF-beta-related neurotrophic factor receptor 2
    • TRN receptor GPI anchored
    • TRNR 2
    • TRNR2
    see all
  • Function
    Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
    Isoform 2: Participates to NRTN-induced 'Ser-727' phosphorylation of STAT3.
  • Tissue specificity
    Isoform 1 is found in both brain and placenta.
  • Sequence similarities
    Belongs to the GDNFR family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

References

ab39769 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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