Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-YGQPSTKHYVTS
    • Amino acids
      540 to 551

Associated products

Specifications

Our Abpromise guarantee covers the use of ab23022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-GERP antibody (ab4302)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • AA408830
    • BB006755
    • Glioblastoma-expressed RING finger protein
    • Lioblastoma expressed ring finger protein
    • Probable E3 ubiquitin-protein ligase TRIM8
    • RING finger protein 27
    • RNF27
    • RP11-47A8.4
    • TRIM8
    • TRIM8_HUMAN
    • Tripartite motif containing 8
    • Tripartite motif protein TRIM8
    • Tripartite motif-containing protein 8
    see all
  • Function
    Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1.
  • Tissue specificity
    Widely expressed.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Belongs to the TRIM/RBCC family.
    Contains 2 B box-type zinc fingers.
    Contains 1 RING-type zinc finger.
  • Domain
    The coiled coil domain is required for homodimerization.
    The region immediately C-terminal to the RING motif is sufficient to mediate the interaction with SOCS1.
  • Information by UniProt

References

ab23022 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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