Human Glucose Transporter GLUT2 peptide (ab105630)

Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab105630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Glucose Transporter GLUT2 antibody (ab95256)

  • Purity
    70 - 90% by HPLC.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Glucose Transporter 2
    • Glucose Transporter GLUT2
    • Glucose transporter type 2
    • Glucose transporter type 2 liver
    • Glucose transporter, liver/islet
    • GLUT-2
    • GLUT2
    • GTR2_HUMAN
    • GTT2
    • liver
    • SLC2A2
    • Solute carrier family 2 (facilitated glucose transporter) member 2
    • Solute carrier family 2 facilitated glucose transporter member 2
    • Solute carrier family 2, facilitated glucose transporter member 2
    see all
  • Function
    Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
  • Tissue specificity
    Liver, insulin-producing beta cell, small intestine and kidney.
  • Involvement in disease
    Fanconi-Bickel syndrome
  • Sequence similarities
    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • Post-translational
    modifications
    N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.
  • Cellular localization
    Membrane.
  • Information by UniProt

References for Human Glucose Transporter GLUT2 peptide (ab105630)

ab105630 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Application
Western blot
We have used whole kidney lysate form normoglycemic mice or STZ induced diabetic mice after 16 weeks from injection.

Application: Western blot
Sample: whole Kidney lysate
Gel Running Conditions: Reduced Denaturing
Loading amount: 30 µg

Treatment: Five consecutive intraperitoneal Strreptozotocin injections (Cayman Chemical 50 mg/kg per day), Samples from kidneys after 16 weeks from last injection.
Specification: Mouse Kidney
Blocking step: Milk as blocking agent for 1 hour, Temperature: 25°C

First antibody (ab95256) with/ without Blocking peptide (ab105630), ratio 1:10-
Incubation time 16 hour(s) , Temperature: 4°C
Dilution 1/1000

Secondary antibody
Dilution 1/10000
Name ab97085
Host species: Rabbit
Clonality: Polyclonal
Conjugation: Horse Radish Peroxidase
Detection
Detection method ECL+
Exposure 2 minute(s) and 0 second(s)


lanes 1-3, 7-9 are from WT normoglycemic mice
lanes 4-6, 10-12 are from STZ induced diabetic mice

lanes 1-6 with ab95256
lanes 7-12 with ab95256+ ab105630

STZ- Streptozotocine
bp- Blocking peptide
Username

Shiran Udi

Verified customer

Submitted Jul 03 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up