Human Glucose Transporter GLUT4 peptide (ab34088)

Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab34088 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Glucose Transporter GLUT4 antibody (ab33780)

  • FormLiquid
  • Additional notes

    ab34088 is the blocking peptide for antibody ab33780, ab65267 and ab48547.

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Glucose transporter GLUT 4
    • Glucose transporter type 4
    • Glucose transporter type 4 insulin responsive
    • GLUT 4
    • GLUT-4
    • GLUT4
    • GTR4_HUMAN
    • Insulin responsive glucose transporter type 4
    • insulin-responsive
    • kug
    • SLC 2A4
    • SLC2A4
    • solute carrier family 2 (facilitated glucose transporter) member 4
    • Solute carrier family 2 member 4
    • Solute carrier family 2, facilitated glucose transporter member 4
    see all
  • FunctionInsulin-regulated facilitative glucose transporter.
  • Tissue specificitySkeletal and cardiac muscles; brown and white fat.
  • Involvement in diseaseDiabetes mellitus, non-insulin-dependent
  • Sequence similaritiesBelongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • Post-translational
    modifications
    Sumoylated.
  • Cellular localizationCell membrane. Endomembrane system. Cytoplasm, perinuclear region. Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration.
  • Information by UniProt

References for Human Glucose Transporter GLUT4 peptide (ab34088)

ab34088 has not yet been referenced specifically in any publications.

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