Human glutathione S transferase Omega 1 full length protein (ab83166)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab83166 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

  • FormLiquid
  • Additional Notes


    A polymorphism causing an alanine-to-aspartate (A140D) substitution in amino acid 140 produces a variant with lowered enzyme activities in the arsenic biotransformation.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 1x Laemmli Buffer (2.5% Glycerol, 1% SDS, 0.1% Bromophenol blue, 50mM DTT, 25mM Tris HCl, pH 6.8)

General info

  • Alternative names
    • AA407097
    • AI194287
    • AU018802
    • DKFZp686H13163
    • EC 2.5.1.18
    • Glutathione S transferase omega 1
    • Glutathione S-transferase omega
    • Glutathione S-transferase omega 1-1
    • Glutathione S-transferase omega-1
    • Glutathione transferase omega 1
    • Glutathione-dependent dehydroascorbate reductase
    • Glutathione-S-transferase like
    • Glutathione-S-transferase omega 1
    • GSTO 1-1
    • GSTO-1
    • GSTO1
    • GSTO1 1
    • GSTO1_HUMAN
    • GSTTLp28
    • GSTX
    • Gtsttl
    • MGC94845
    • MMA(V) reductase
    • Monomethylarsonic acid reductase
    • OTTHUMP00000020429
    • p28
    • S-(Phenacyl)glutathione reductase
    • SPG-R
    see all
  • FunctionExhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.
  • Tissue specificityUbiquitous. Highest expression in liver, pancreas, skeletal muscle, spleen, thymus, colon, blood leukocyte and heart. Lowest expression in brain, placenta and lung.
  • Sequence similaritiesBelongs to the GST superfamily. Omega family.
    Contains 1 GST C-terminal domain.
    Contains 1 GST N-terminal domain.
  • Cellular localizationCytoplasm > cytosol.
  • Target information above from: UniProt accession P78417 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Human glutathione S transferase Omega 1 full length protein (ab83166)

ab83166 has not yet been referenced specifically in any publications.

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