Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVL

Associated products

Specifications

Our Abpromise guarantee covers the use of ab111665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Glypican 3 antibody (ab66596)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • DGSX
    • Glypican proteoglycan 3
    • Glypican-3 [Precursor]
    • Gpc3
    • GPC3_HUMAN
    • GTR2 2
    • GTR2-2
    • Heparan sulphate proteoglycan
    • Intestinal protein OCI 5
    • Intestinal protein OCI-5
    • MXR7
    • OCI 5
    • OCI-5
    • OCI5
    • SDYS
    • Secreted glypican-3
    • SGB
    • SGBS
    • SGBS1
    see all
  • FunctionCell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition.
  • Tissue specificityHighly expressed in lung, liver and kidney.
  • Involvement in diseaseDefects in GPC3 are the cause of Simpson-Golabi-Behmel syndrome type 1 (SGBS1) [MIM:312870]; also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
  • Sequence similaritiesBelongs to the glypican family.
  • Cellular localizationCell membrane and Secreted > extracellular space.
  • Information by UniProt

References for Human Glypican 3 peptide (ab111665)

ab111665 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111665.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"