For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
- Amino Acid Sequence
Amino acids 2 to 21 of human DFF45/35 (1)
- Amino acids2 to 21
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
PBS with 0.1% BSA 0.02% sodium azide pH7.2
- Caspase activated deoxyribonuclease inhibitor short form
- DFF 1
- FunctionInhibitor of the caspase-activated DNase (DFF40).
- Sequence similaritiesContains 1 CIDE-N domain.
modificationsCaspase-3 cleaves DFF45 at 2 sites to generate an active factor.
Phosphorylated upon DNA damage, probably by ATM or ATR.
- Cellular localizationCytoplasm.
Information by UniProt
References for Human ICAD peptide (ab8442)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"