Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFK

Associated products

Specifications

Our Abpromise guarantee covers the use of ab111673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-IDH2 antibody (ab84726)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • D2HGA2
    • ICD-M
    • IDH
    • IDH2
    • IDHM
    • IDHP_HUMAN
    • IDP
    • IDPM
    • Isocitrate dehydrogenase [NADP], mitochondrial
    • Isocitrate dehydrogenase 2 (NADP+), mitochondrial
    • mNADP-IDH
    • NADP(+)-specific ICDH
    • Oxalosuccinate decarboxylase
    see all
  • FunctionPlays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex.
  • Involvement in diseaseD-2-hydroxyglutaric aciduria 2
    Glioma
    enetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma.
  • Sequence similaritiesBelongs to the isocitrate and isopropylmalate dehydrogenases family.
  • Post-translational
    modifications
    Acetylation at Lys-413 dramatically reduces catalytic activity. Deacetylated by SIRT3.
  • Cellular localizationMitochondrion.
  • Information by UniProt

References for Human IDH2 peptide (ab111673)

ab111673 has not yet been referenced specifically in any publications.

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