Anti-Human IgG antibody [3D3] (ab7498)

Overview

  • Product nameAnti-Human IgG antibody [3D3]
    See all Human IgG primary antibodies
  • Description
    Mouse monoclonal [3D3] to Human IgG
  • SpecificityClass-specific for human IgG. No allotype restriction. Fc-region specific. Relatively high affinity. No cross-reactivity with human IgA, IgM, IgE.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    These clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunised with IgG from human serum.

  • General notesConcentration varies from lot to lot and can be provided on request.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number3D3
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab7498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notesSpecific antibody titer is 1/100000 by indirect ELISA.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceIgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • FLJ39988 antibody
      • FLJ40036 antibody
      • FLJ40253 antibody
      • FLJ40587 antibody
      • FLJ40789 antibody
      • FLJ40834 antibody
      • G1m marker antibody
      • G2m marker antibody
      • G3m marker antibody
      • G4m marker antibody
      • HDC antibody
      • Heavy chain disease protein antibody
      • Human immunglobulin G antibody
      • Ig gamma 1 chain C region antibody
      • Ig gamma 2 chain C region antibody
      • Ig gamma 3 chain C region antibody
      • Ig gamma 4 chain C region antibody
      • IgG heavy chain locus antibody
      • IGHG 1 antibody
      • IGHG 2 antibody
      • IGHG 3 antibody
      • IGHG 4 antibody
      • IGHG1 antibody
      • IGHG2 antibody
      • IGHG3 antibody
      • IGHG4 antibody
      • Immunoglobulin Gm1 antibody
      • Immunoglobulin Gm3 antibody
      • Immunoglobulin Gm4 antibody
      • immunoglobulin heavy constant gamma 1 (G1m marker) antibody
      • Immunoglobulin heavy constant gamma 1 antibody
      • immunoglobulin heavy constant gamma 2 (G2m marker) antibody
      • Immunoglobulin heavy constant gamma 2 antibody
      • immunoglobulin heavy constant gamma 3 (G3m marker) antibody
      • Immunoglobulin heavy constant gamma 3 antibody
      • immunoglobulin heavy constant gamma 4 (G4m marker) antibody
      • Immunoglobulin heavy constant gamma 4 antibody
      • MGC117419 antibody
      • MGC45809 antibody
      see all

    References for Anti-Human IgG antibody [3D3] (ab7498)

    ab7498 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. For both these antibodies the concentration varies from lot to lot; normally the concentration is from 1 to 10 mg/ml. We are currently out of stock for both of these; if you were to order one, I could obtain more information...

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    Regarding ab7498, this particular clone is Fc-specific but the epitope has not been more precisely determined. For ab771, the epitope is unknown. If you have any more questions, please contact us again.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"