Anti-Human IgG4 heavy chain antibody [5C7] (ab1930)

Overview

  • Product name
    Anti-Human IgG4 heavy chain antibody [5C7]
    See all Human IgG4 heavy chain primary antibodies
  • Description
    Mouse monoclonal [5C7] to Human IgG4 heavy chain
  • Specificity
    Subclass-specific for human IgG4. No allotype restriction. Fc-region specific.
  • Tested applications
    Suitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    IgG4 from human serum.

  • General notes
    Concentration varies from lot to lot and can be provided on request.

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.40
    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Purification notes
    Chromatography on protein A Sepharose
  • Clonality
    Monoclonal
  • Clone number
    5C7
  • Myeloma
    Sp2/0
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab1930 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notes
    ELISA: Use at an assay dependent dilution. Specific antibody titer is 1/100000 by indirect ELISA

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      Immunoglobulin G (IgG), is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
    • Cellular localization
      Secreted
    • Database links
    • Alternative names
      • AU044919 antibody
      • Gamma 2b immunoglobulin antibody
      • Ig gamma 4 chain C region antibody
      • Ighg 4 antibody
      • Ighg4 antibody
      • Immunoglobulin gamma 4 heavy chain antibody
      • Immunoglobulin heavy chain (gamma polypeptide 4) antibody
      • Immunoglobulin heavy chain gamma polypeptide antibody
      • Immunoglobulin heavy constant gamma 4 (G4m marker) antibody
      • MGC102604 antibody
      • MGC102659 antibody
      see all

    References

    This product has been referenced in:
    • Medeiros MM  et al. Natural antibody response to Plasmodium falciparum merozoite antigens MSP5, MSP9 and EBA175 is associated to clinical protection in the Brazilian Amazon. BMC Infect Dis 13:608 (2013). ELISA ; Human . Read more (PubMed: 24373342) »

    See 1 Publication for this product

    Customer reviews and Q&As

    The concentration of the antibody is 7 mg/ml.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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