Human IKB epsilon protein fragment (ab91869)
- Product nameHuman IKB epsilon protein fragment
- SourceE. coli
- Amino Acid Sequence
- SequenceSRALQDRHGDTALHVACQRQHLACARCLLEGRPEPGRGTS HSLDLQLQNWQGLACLHIAT LQKNQPLMELLLRNGADI DVQEGTSGKTALHLAVETQERGLVQFLLQAGAQVDARMLN GC TPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQ DLTEESLVLLPFDDLKISGKLLLCTD
- Amino acids319 to 500
Our Abpromise guarantee covers the use of ab91869 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Concentration information loading...
Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
- ReconstitutionReconstitute with 92 µl aqua dest.
- I kappa B epsilon
- IkB E
- NF kappa B inhibitor epsilon
- NF kappa BIE
- NF-kappa-B inhibitor epsilon
- NFkappa BIE
- NFkappaB inhibitor epsilon
- Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor epsilon
- solute carrier family 35, member B2
- FunctionInhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
- Tissue specificityHighly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages.
- Sequence similaritiesBelongs to the NF-kappa-B inhibitor family.
Contains 6 ANK repeats.
modificationsSerine phosphorylated; followed by proteasome-dependent degradation.
- Cellular localizationCytoplasm.
Human IKB epsilon protein fragment images
The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.
References for Human IKB epsilon protein fragment (ab91869)
ab91869 has not yet been referenced specifically in any publications.