Human Integrin beta 4 (phospho Y1526) peptide (ab42719)



  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • Modificationsphospho Y1526

Associated products


Our Abpromise guarantee covers the use of ab42719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThis peptide is found in all three Integrin beta 4 isoforms and is highly conserved in rat and mouse Integrin beta 4.
  • Applications

    Blocking - Blocking peptide for Anti-Integrin beta 4 (phospho Y1526) antibody (ab29044)


  • FormLiquid
  • Additional notesThe concentration of this peptide is specified on the datasheet.This peptide is found in all three Integrin beta 4 isoforms and is highly conserved in rat and mouse Integrin beta 4.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.05% Sodium Azide
    Constituents: PBS

General Info

  • Alternative names
    • CD 104
    • CD104
    • CD104 antigen
    • gp150
    • Integrin beta 4 subunit
    • Integrin beta-4
    • ITB4_HUMAN
    • ITG B4
    • ITGB 4
    • Itgb4
    see all
  • FunctionIntegrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells.
  • Tissue specificityIntegrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.
  • Involvement in diseaseDefects in ITGB4 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) [MIM:226730]; also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. EB-PA is an autosomal recessive, frequently lethal, epidermolysis bullosa with variable involvement of skin, nails, mucosa, and with variable effects on the digestive system. It is characterized by mucocutaneous fragility, aplasia cutis congenita, and gastrointestinal atresia, which most commonly affects the pylorus. Pyloric atresia is a primary manifestation rather than a scarring process secondary to epidermolysis bullosa.
    Defects in ITGB4 are a cause of generalized atrophic benign epidermolysis bullosa (GABEB) [MIM:226650]. GABEB is a non-lethal, adult form of junctional epidermolysis bullosa characterized by life-long blistering of the skin, associated with hair and tooth abnormalities.
  • Sequence similaritiesBelongs to the integrin beta chain family.
    Contains 1 Calx-beta domain.
    Contains 4 fibronectin type-III domains.
    Contains 1 PSI domain.
    Contains 1 VWFA domain.
  • DomainThe fibronectin type-III-like domains bind BPAG1 and plectin and probably also recruit BP230.
  • Cellular localizationMembrane.
  • Information by UniProt

References for Human Integrin beta 4 (phospho Y1526) peptide (ab42719)

ab42719 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab42719.
Please use the links above to contact us or submit feedback about this product.