Human intestinal FABP full length protein (ab115502)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • AccessionP12104
    • SpeciesHuman
    • SequenceMKHHHHHHASAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTI TQEGNKFTVKESSAFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLI GKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD
    • Molecular weight16 kDa including tags
    • Amino acids2 to 131
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab115502 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Endotoxin level< 1.000 Eu/µg
  • Purity> 95 % by SDS-PAGE.
    ab115502 is purified using Ni-NTA chromatography.
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Store at -80°C

    pH: 7.40
    Constituents: 0.29% Sodium chloride, 0.69% Phosphate Buffer

  • ReconstitutionAdd deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at –80°C for long term storage. Reconstituted protein can be stored at 4°C for a week.

General info

  • Alternative names
    • FABP 2
    • FABP2
    • FABPI
    • FABPI_HUMAN
    • Fatty acid binding protein
    • Fatty acid binding protein 2 intestinal
    • Fatty acid binding protein intestinal
    • Fatty acid-binding protein
    • Fatty acid-binding protein 2
    • I FABP
    • I-FABP
    • IFABP
    • intestinal
    • Intestinal fatty acid binding protein 2
    • Intestinal-type fatty acid-binding protein
    • MGC133132
    • OTTHUMP00000163925
    see all
  • FunctionFABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
  • Tissue specificityExpressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
  • Sequence similaritiesBelongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • DomainForms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • Cellular localizationCytoplasm.
  • Information by UniProt

Human intestinal FABP full length protein images

  • 14% SDS-PAGE showing ab115502
    Lane 1: M.W. marker – 14, 21, 31, 45, 66, 97 kDa
    Lane 2: reduced and boiled sample, 5µg/lane.
    Lane 3: non-reduced and non-boiled sample, 5µg/lane.

References for Human intestinal FABP full length protein (ab115502)

ab115502 has not yet been referenced specifically in any publications.

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