Human Iroquois homeobox protein 3 peptide (ab26906)

Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab26906 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • AI894186
    • Homeodomain protein IRXB1
    • Iroquois class homeodomain protein IRX 1
    • Iroquois homeobox 3
    • Iroquois homeobox protein 3
    • Iroquois-class homeodomain protein irx-3
    • IRX 1
    • irx3
    • IRX3_HUMAN
    • IRXB1
    see all
  • FunctionTranscription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells.
  • Sequence similaritiesBelongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human Iroquois homeobox protein 3 peptide (ab26906)

ab26906 has not yet been referenced specifically in any publications.

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