• NatureSynthetic


Our Abpromise guarantee covers the use of ab21996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Islet 1 antibody - Neural Stem Cell Marker (ab20670)

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • Insulin gene enhancer protein ISL 1
    • Insulin gene enhancer protein ISL-1
    • Insulin related protein
    • ISL 1
    • ISL LIM homeobox 1
    • ISL1
    • ISL1 transcription factor LIM homeodomain
    • ISL1 transcription factor, LIM/homeodomain
    • ISL1 transcription factor, LIM/homeodomain (islet 1)
    • ISL1_HUMAN
    • Islet-1
    • Islet1
    see all
  • FunctionBinds to one of the cis-acting domain of the insulin gene enhancer.
  • Tissue specificityExpressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
  • Sequence similaritiesContains 1 homeobox DNA-binding domain.
    Contains 2 LIM zinc-binding domains.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human Islet 1 peptide (ab21996)

This product has been referenced in:
  • Moreno N  et al. Characterization of the bed nucleus of the stria terminalis in the forebrain of anuran amphibians. J Comp Neurol 520:330-63 (2012). Read more (PubMed: 21674496) »
  • Moreno N  et al. Islet1 as a marker of subdivisions and cell types in the developing forebrain of Xenopus. Neuroscience 154:1423-39 (2008). Read more (PubMed: 18515014) »

See all 2 Publications for this product

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