Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • AccessionQ96N16
    • SpeciesHuman
    • Molecular weight19 kDa
    • Amino acids282 to 436
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127233 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • ReconstitutionReconstitute with water to desired concentration.

General info

  • Alternative names
    • FLJ31564
    • GABA B receptor binding protein
    • GABA-B receptor-binding protein
    • GABABRBP
    • Jak and microtubule interacting protein 1
    • JAKMIP 1
    • JAKMIP1
    • JAMIP1
    • Janus kinase and microtubule interacting protein 1
    • Janus kinase and microtubule-interacting protein 1
    • JKIP1_HUMAN
    • Marlin 1
    • Marlin-1
    • MARLIN1
    • Multiple alpha-helices and RNA-linker protein 1
    • Multiple coiled coil GABABR1 binding protein
    • OTTHUMP00000155144
    • OTTHUMP00000203209
    • OTTHUMP00000203210
    • OTTHUMP00000203212
    • OTTHUMP00000217225
    • OTTHUMP00000217781
    see all
  • FunctionAssociates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
  • Tissue specificityPredominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.
  • Sequence similaritiesBelongs to the JAKMIP family.
  • Cellular localizationCytoplasm > cytoskeleton. Membrane. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.
  • Information by UniProt

References for Human JAKMIP1 protein fragment (ab127233)

ab127233 has not yet been referenced specifically in any publications.

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