Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • AccessionP33176
    • SpeciesHuman
    • SequenceC-QPVAVRGGGGKQV
    • Amino acids951 to 963

Specifications

Our Abpromise guarantee covers the use of ab23262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • Conventional kinesin heavy chain
    • KIF 5B
    • KIF5B
    • Kinesin 1
    • kinesin 1 (110-120kD)
    • Kinesin 1 heavy chain
    • Kinesin family member 5B
    • Kinesin heavy chain
    • kinesin, heavy chain, ubiquitous
    • Kinesin-1 heavy chain
    • Kinesin1
    • KINH
    • KINH_HUMAN
    • KNS
    • KNS 1
    • KNS1
    • Ubiquitous kinesin heavy chain
    • UKHC
    see all
  • FunctionMicrotubule-dependent motor required for normal distribution of mitochondria and lysosomes.
  • Sequence similaritiesBelongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily.
    Contains 1 kinesin motor domain.
  • DomainComposed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.
  • Cellular localizationCytoplasm, cytoskeleton. Uniformly distributed between soma and neurites in hippocampal neurons.
  • Information by UniProt

References for Human KIF5B peptide (ab23262)

ab23262 has not yet been referenced specifically in any publications.

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