The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
competitive binding assays
Blocking - Blocking peptide for Anti-Kinesin 5C antibody (ab5630)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Kinesin family member 5C
Kinesin heavy chain isoform 5C
Kinesin heavy chain neuron specific
Kinesin heavy chain neuron specific 2
Kinesin heavy chain neuron-specific 2
FunctionKinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.
Tissue specificityHighest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary.
Sequence similaritiesBelongs to the kinesin-like protein family. Kinesin subfamily. Contains 1 kinesin-motor domain.
DomainComposed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.