Human LXR alpha + LXR beta peptide (ab45625)

Overview

  • Product nameHuman LXR alpha + LXR beta peptide

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • Sequence(C)RLQDKKLPPLLSEI
    • Amino acids440 to 456

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-LXR alpha + LXR beta antibody (ab24362)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Constituent: dH2O

General Info

  • Alternative names
    • Liver X receptor alpha
    • Liver X receptor beta
    • LXR a
    • LXR b
    • LXRalpha
    • LXRbeta
    • NR1H2
    • NR1H3
    • Nuclear orphan receptor LXR alpha
    • Nuclear orphan receptor LXR beta
    • Nuclear receptor subfamily 1 group H member 2
    • Nuclear receptor subfamily 1 group H member 3
    • Oxysterols receptor LXR alpha
    • Oxysterols receptor LXR beta
    see all
  • RelevanceLXR alpha and LXR beta are orphan receptors. Interaction with RXR shifts RXR from its role as a silent DNA binding partner to an active ligand binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4 type response elements characterized by direct repeats of two similar hexanuclotide half sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis. LXR alpha: Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals. LXR beta: Ubiquitously expressed.
  • Cellular localizationNuclear

References for Human LXR alpha + LXR beta peptide (ab45625)

ab45625 has not yet been referenced specifically in any publications.

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