The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-LXR beta antibody (ab24361)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Liver X nuclear receptor beta
Liver X receptor beta
LX receptor beta
Nuclear orphan receptor LXR beta
Nuclear receptor NER
Nuclear receptor subfamily 1 group H member 2
Oxysterols receptor LXR-beta
Steroid hormone nuclear receptor NER
Ubiquitously-expressed nuclear receptor
FunctionOrphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.