Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceC-QEHSYSHGGGAWL
    • Amino acids194 to 206

Associated products

Specifications

Our Abpromise guarantee covers the use of ab22975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-MAD3 antibody (ab3995)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

General Info

  • Alternative names
    • bHLHc13
    • Class C basic helix-loop-helix protein 13
    • FLJ35523
    • Likely ortholog of mouse Max dimerization protein 3
    • MAD3_HUMAN
    • MAX dimerization protein 3
    • Max dimerizer 3
    • Max-associated protein 3
    • Max-interacting transcriptional repressor MAD3
    • MGC2383
    • mxd3
    • Myx
    • OTTHUMP00000223596
    • OTTHUMP00000223598
    see all
  • FunctionTranscriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
  • Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Human MAD3 peptide (ab22975)

ab22975 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"