Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    Blocking - Blocking peptide for Anti-MAP1 antibody (ab25954)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

General Info

  • Alternative names
    • MAP 1
    • MAP-1
    • MAP1
    • MOAP1
    • MOAP1_HUMAN
    • Modulator of Apoptosis
    • Modulator of apoptosis 1
    • Paraneoplastic antigen like 4
    • Paraneoplastic antigen Ma4
    • paraneoplastic Ma antigen family member 4
    • PNMA4
    see all
  • Function
    Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
  • Tissue specificity
    Ubiquitously expressed with higher levels in heart and brain.
  • Sequence similarities
    Belongs to the PNMA family.
  • Domain
    The BH3-like domain is required for association with BAX and for mediating apoptosis. The three BH domains (BH1, BH2, and BH3) of BAX are all required for mediating protein-protein interaction.
  • Information by UniProt

References

ab39806 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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